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1.
Clin Case Rep ; 9(10): e05032, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1487452

ABSTRACT

A 45-year-old woman with a history of Henoch-Schönlein (HSP) purpura received COVID-19 vaccination. The patient showed HSP reactivation after COVID-19 vaccination and booster. In HSP, autoimmune memory of vasculitis persists and might be reactivated with COVID-19 vaccination.

3.
Clin Case Rep ; 9(8): e04700, 2021 Aug.
Article in English | MEDLINE | ID: covidwho-1372704

ABSTRACT

The administration of glucocorticoid and hydroxychloroquine (HCQ) may be able to control systemic lupus erythematosus (SLE) activities under COVID-19 infection by suppress the cytokine storm.

4.
Intern Med ; 60(4): 639-643, 2021 Feb 15.
Article in English | MEDLINE | ID: covidwho-1082267

ABSTRACT

The coronavirus disease 2019 (COVID-19) pandemic has become an urgent global health issue. An older age and underlying conditions, such as diabetes, have been reported as risk factors, but whether or not autoimmune diseases increase the risk remains unknown. An 85-year-old man with Sjögren's syndrome developed a severe COVID-19 infection that required oxygen supplementation. After discussing the goals of care with him and his wife, off-label tocilizumab was given concomitantly, resulting in a rapid improvement in his symptoms and respiratory failure. This patient represents a supplementary case confirming the efficacy and safety of tocilizumab for COVID-19 in elderly patients with autoimmune diseases.


Subject(s)
Antibodies, Monoclonal, Humanized/therapeutic use , COVID-19/complications , Off-Label Use , Respiratory Distress Syndrome/drug therapy , Sjogren's Syndrome/complications , Adrenal Cortex Hormones/therapeutic use , Aged, 80 and over , Anti-Inflammatory Agents/therapeutic use , COVID-19/immunology , Cytokine Release Syndrome , Drug Therapy, Combination , Dyspnea/etiology , Humans , Male , Pandemics , Respiratory Distress Syndrome/etiology , Respiratory Insufficiency/drug therapy , SARS-CoV-2
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